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Analyzing the Shift: Examining the Trends in Cancer Mortality vs. Incidence

The American Cancer Society’s Cancer Statistics, 2025 report shows a 34% decline in U.S. cancer mortality from 1991 to 2022, averting 4.5 million deaths due to reduced smoking, early detection, and better treatments. However, rising cancer incidence among younger and middle-aged women, along with persistent racial disparities, pose challenges. Native Americans face the highest cancer mortality, and Black individuals have significantly higher rates for prostate, stomach, breast, and uterine cancers. Women under 50 also see an 82% higher incidence than men. Addressing systemic inequalities in cancer care is crucial to closing these gaps and improving outcomes for all populations.

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